Current Issue : January-March Volume : 2021 Issue Number : 1 Articles : 1 Articles
Due to the limited therapeutic index and the intrinsic toxicity of anticancer drugs, drug reactions in oncology are of special concern. Interactions with other drugs could trigger slight differences in the chemotherapy agent's pharmacokinetics or pharmacodynamic, which may dramatically affect its effectiveness or toxicity. Precise data are not available, but the occurrence of drug-drug interactions in oncology is theorized to be higher than in most other conditions. The identification of potentially clinically important drug reactions has been made possible by advances in in-vitro approaches and early clinical research. Typically, cancer patients take a number of medications to manage related conditions, such as pain and nausea. The types of drug interactions that arise in oncology, the pathways causing these interactions and selected examples are illustrated....
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